- In
organic chemistry,
thioesters are
organosulfur compounds with the
molecular structure R−C(=O)−S−R’. They are
analogous to
carboxylate esters (R−C(=O)−O−R’)...
-
Fatty acid
synthase (FAS) is an
enzyme that in
humans is
encoded by the FASN gene.
Fatty acid
synthase is a multi-enzyme
protein that
catalyzes fatty acid...
-
Thioester containing protein 1,
often called TEP1 is a key
component of the
arthropod innate immune system. TEP1 was
first identified as a key immunity...
- N-terminal
cysteine residue of an
unprotected peptide attacks the C-terminal
thioester of a
second unprotected peptide, in an
aqueous buffer at pH 7.0 and room...
- β-mercaptoethylamine group. This
thioester linkage is a "high energy" bond,
which is
particularly reactive.
Hydrolysis of the
thioester bond is
exergonic (−31.5 kJ/mol)...
-
coenzyme A as a substrate, and
around 4% of
cellular enzymes use it (or a
thioester) as a substrate. In humans, CoA
biosynthesis requires cysteine, pantothenate...
-
conformational change cause thioester hydrolysis and
release coenzyme A. This
ensures that the
energy released from the
thioester bond
cleavage will drive...
- It can be
prepared by
oxidation of 2,4-dichlorotoluene. The
coenzyme A
thioester of 2,4-dichlorobenzoic acid is the
substrate for 2,4-dichlorobenzoyl reductase...
-
Hydrolysis of
salts of
secondary nitro compounds ( Nef reaction)
Alkylation of
thioester with
organozinc compounds (****uyama coupling).
Alkylation of acid chloride...
- of this
enzyme class is acetyl-CoA:2-oxoglutarate C-acetyltransferase (
thioester-hydrolysing,
carboxymethyl forming).
Other names in
common use include...
