-
Sphingolipids are a
class of
lipids containing a
backbone of
sphingoid bases,
which are a set of
aliphatic amino alcohols that
includes sphingosine. They...
-
cleavage products:
saposins A, B, C, and D.
Saposin is an
acronym for
Sphingolipid Activator PrO[S]teINs. Each
domain of the
precursor protein is approximately...
- with an
unsaturated hydrocarbon chain,
which forms a
primary part of
sphingolipids, a
class of cell
membrane lipids that
include sphingomyelin, an important...
- bilayer.
Contrary to
previous ****umptions that
ceramides and
other sphingolipids found in cell
membrane were
purely supporting structural elements, ceramide...
-
sphingosine backbone. Alternatively, this sphingosine-derived
lipid (
sphingolipid) can be
synthesized from
scratch (de novo) by the
enzymes serine palmitoyl...
-
formation sphingosine-1-phosphate (S1P) from the
precursor sphingolipid sphingosine.
Sphingolipid metabolites, such as ceramide,
sphingosine and sphingosine-1-phosphate...
-
ORMDL sphingolipid biosynthesis regulator 1 is a
protein that in
humans is
encoded by the ORMDL1 gene. GRCh38:
Ensembl release 89: ENSG00000128699 – Ensembl...
- Palmitoyl-CoA is also the
starting substrate,
along with serine, for
sphingolipid biosynthesis.
Palmitoyl CoA and
serine parti****te in a condensation...
- Delta8-fatty-acid
desaturase (EC 1.14.19.4, Delta8-
sphingolipid desaturase, EFD1, BoDES8, SLD, Delta8
fatty acid desaturase, Delta8-desaturase) is an enzyme...
-
ORMDL sphingolipid biosynthesis regulator 3 is a
protein that in
humans is
encoded by the ORMDL3 gene.
Variants affecting the
expression of this gene are...
