-
Sortase refers to a
group of
prokaryotic enzymes that
modify surface proteins by
recognizing and
cleaving a carboxyl-terminal
sorting signal. For most...
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Sortase A (EC 3.4.22.70, SrtA, SrtA protein, SrtA
sortase) is an enzyme. This
enzyme catalyses a cell wall
sorting reaction, in
which a
surface protein...
-
Sortases are
membrane anc****d
enzyme that sort
these surface proteins onto the
bacterial cell
surface and
anchor them to the peptidoglycan.
There are...
- Nikghalb,
Kevyan D. (2018). "Expanding the
Scope of
Sortase-Mediated
Ligations by
Using Sortase Homologues". ChemBioChem. 19 (7): 185–195. doi:10.1002/cbic...
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aspect that
distinguishes sortases in
general is that they have a very
specific targeting for
their substrate, as
sortases have
generally two functions...
-
enzyme D-glutamyl
transpeptidase A protein-sorting
transpeptidase (e.g.
sortase), that
cleaves a C-terminal
sorting signal from its
target protein(s) and...
-
pentaglycine bridges (chains of five
glycine residues) by the
transpeptidase sortase A.
Protein A, an IgG-binding protein,
binds to the Fc
region of an antibody...
-
include the use of
split inteins,
spontaneous isopeptide bond
formation and
sortase ligation. In
order to
optimize synthesis of long peptides, a
method was...
- C15 Pyroglutamyl-peptidase I (Bacillus amyloliquefaciens) CL C60, C82
Sortase A (Staphylococcus aureus) CM C18
Hepatitis C
virus peptidase 2 (hepatitis...
- (hence the name "toxin
mediated pilus").
Bacterial nanowires Flagellum Sortase P
fimbriae PilZ
domain "pilus" at Dorland's
Medical Dictionary Brinton...
