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Sortase refers to a
group of
prokaryotic enzymes that
modify surface proteins by
recognizing and
cleaving a carboxyl-terminal
sorting signal. For most...
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Sortase A (EC 3.4.22.70, SrtA, SrtA protein, SrtA
sortase) is an enzyme. This
enzyme catalyses a cell wall
sorting reaction, in
which a
surface protein...
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Sortases are
membrane anc****d
enzyme that sort
these surface proteins onto the
bacterial cell
surface and
anchor them to the peptidoglycan.
There are...
- Nikghalb,
Kevyan D. (2018). "Expanding the
Scope of
Sortase-Mediated
Ligations by
Using Sortase Homologues". ChemBioChem. 19 (7): 185–195. doi:10.1002/cbic...
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aspect that
distinguishes sortases in
general is that they have a very
specific targeting for
their substrate, as
sortases have
generally two functions...
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pentaglycine bridges (chains of five
glycine residues) by the
transpeptidase sortase A.
Protein A, an IgG-binding protein,
binds to the Fc
region of an antibody...
- A protein-sorting
transpeptidase is an enzyme, such as the
sortase SrtA of
Staphylococcus aureus, that
cleaves one or more
target proteins produced by...
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anchor motif of
surface proteins similar to
Sortase. However,
LPXTGase differs significantly from
Sortase in
several ways: a) it is glycosylated, b) it...
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signal PEP-CTERM. The name
derives from a
predicted role
analogous to
sortase,
despite the lack of any
detectable sequence homology, and a
strong ****ociation...
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bacteria are
cleaved between the T and G
residue in the
LPXTG sortase signal by the
enzyme sortase (the
enzyme was not
discovered yet, but was
later shown by...
