-
Papin C, Limbourg-Bouchon B,
Rouyer F (November 2002). "The F-box
protein slimb controls the
levels of
clock proteins period and timeless". Nature. 420...
- (Figure 2). The
Drosophila protein Slimb is part of an SCF
complex that
targets proteins for ubiquitylation.
Slimb binds to
phosphorylated Ci protein...
- repeat-containing
protein 1A (FBXW1A) also
known as βTrCP1 or Fbxw1 or hs
Slimb or pIkappaBalpha-E3
receptor subunit is a
protein that in
humans is encoded...
-
inhibits Smoothened. Then
active Smoothened protein is able to
inhibit PKA and
Slimb, so that the Ci
protein is not cleaved. This
intact Ci
protein can enter...
- "to give a signal". Also
possible is
schimmenti "diagonal" from
Gothic slimbs "slanting".
Other sources of
Germanic influences include the Hohenstaufen...
- 1999). "Signal-induced
ubiquitination of
IkappaBalpha by the F-box
protein Slimb/beta-TrCP".
Genes Dev. 13 (3): 284–94. doi:10.1101/gad.13.3.284. PMC 316434...
- ubiquitin-proteasome
pathway and is
carried out by a
ubiquitin ligase called Slimb (supernumerary limbs). At the same time, TIM is
itself phosphorylated by...
-
homologous to
Xenopus βTrCP,
yeast Met30,
Neurospora Scon2 and
Drosophila Slimb. In mammals, in
addition to βTrCP2, a
paralog protein (called βTrCP1 or...
- cells) as
required for
bringing Plk4 to
centrioles and an F-box protein,
Slimb – a
component of the SCF
ubiquitin protein ligase, as
responsible for targeting...
- 1999). "Signal-induced
ubiquitination of
IkappaBalpha by the F-box
protein Slimb/beta-TrCP".
Genes & Development. 13 (3): 284–94. doi:10.1101/gad.13.3.284...
