Definition of Smoothened. Meaning of Smoothened. Synonyms of Smoothened

- Smoothened is a protein that in humans is encoded by the SMO gene. Smoothened is a class Frizzled (class F) G protein-coupled receptor that is a component...
- leads to increased levels of Smoothened is not clear (Step 1 in Figure 3). Following binding of Hh to Patched, Smoothened levels increase greatly over...
- Smoothened agonist (SAG) was one of the first small-molecule agonists developed for the protein Smoothened, a key part of the hedgehog signaling pathway...
- the "Smoothened" protein, by which the Hedgehog signal can be transduced. In the absence of Hedgehog, the Patched receptor inhibits Smoothened action...
- treat cancer. Sonidegib is a Hedgehog signaling pathway inhibitor (via smoothened antagonism). It was approved for medical use in the United States and...
- In statistics and image processing, to smooth a data set is to create an approximating function that attempts to capture important patterns in the data...
- skin together at the middle of it. This is what we call navel today. He smoothened the wrinkles and shaped the chest. But he made sure to leave a few wrinkles...
- protein smoothened. Jervine binds with and inhibits smoothened, which is an integral part of the hedgehog signaling pathways. With smoothened inhibited...
- suppresses the release of another protein called smoothened, and when sonic hedgehog binds PTCH1, smoothened is released and signals cell proliferation. Mutations...
- membrane protein known as smoothened may signal further cascades which impact development. Cyclopamine has a high affinity for smoothened – and upon binding...