-
Ayman W.; Sherif,
Sherif M.; Gaber,
Hatem M. (2003). "The
Chemistry of α-
Haloketones and
Their Utility in
Heterocyclic Synthesis" (PDF). Molecules. 8 (11):...
-
reaction of β-ketoesters (1) with
ammonia (or
primary amines) and α-
haloketones (2) to give
substituted pyrroles (3).
Pyrroles are
found in a variety...
- also
widely used:
Other methods are
known including the
reaction of α-
haloketones and
formamide and the Van
Leusen reaction with
aldehydes and TosMIC....
-
Prominent is the
Hantzsch thiazole synthesis,
which is a
reaction between haloketones and thioamides. For example, 2,4-dimethylthiazole is
synthesized from...
-
decarboxylation of
carboxylic anhydride.
Ketones can be
prepared from
haloketones in
reductive dehalogenation of halo ketones. In
ketonic decarboxylation...
-
reaction of β-ketoesters (1) with
ammonia (or
primary amines) and α-
haloketones (2) to give
substituted pyrroles (3). The
Knorr pyrrole synthesis involves...
- compounds. Similarly,
aminothiazoles can be
synthesized by the
reaction of α-
haloketones and thiourea. The
pharmaceuticals thiobarbituric acid and sulfathiazole...
- some pharmaceuticals, such as dabigatran.
Condensation with
various haloketones provides a
synthetic route to 2,4-disubstituted imidazoles. Armarego...
- (DBPs) that are
present in
traditional pools. Of
highest concern are
haloketones and
trihalomethanes (THMs) of
those the
predominant form
being bro****rm...
-
feature tertiary amines. Such
compounds are
produced by
amination of α-
haloketones and α-haloaldehydes.
Examples include cathinones, methadone, molindone...
