- In chemistry,
acylation is a
broad class of
chemical reactions in
which an acyl
group (R−C=O) is
added to a substrate. The
compound providing the acyl...
-
product is
always less
reactive than the
original molecule, so
multiple acylations do not occur. Also,
there are no
carbocation rearrangements, as the acylium...
- The
Kostanecki acylation is a
method used in
organic synthesis to form
chromones or
coumarins by
acylation of O-hydroxyaryl
ketones with
aliphatic acid...
- S-
acylation is the
process of
chemically linking a
molecule to
another molecule via a
thioester bond.
Protein S-
acylation is a sub-type of S-
acylation where...
- AlCl3 is a
common Lewis-acid
catalyst for Friedel-Crafts reactions, both
acylations and alkylations.
Important products are
detergents and ethylbenzene. These...
-
resolution acylation of amines. With 10 mol% (-)-PPY* in
chloroform at –50 °C, good to very good
selectivities were
observed in the
acylation of amines...
- electrophiles,
which results in the
formation of 1,3-****tones (Stork
acylation). It is also
effective for
activated sp3
alkyl electrophiles, including...
- ketones, such as
those formed in a Friedel-Crafts
acylation. The two-step
sequence of Friedel-Crafts
acylation followed by
Clemmensen reduction constitutes...
- at
temperatures of 60-110 °C.
Direct acylations of
alcohols with
carboxylic acids is
preferred over
acylations with
anhydrides (poor atom economy) or...
- intermediate). Bases, such as
pyridine or N,N-dimethylformamide,
catalyze acylations.
These reagents activate the acyl
chloride via a
nucleophilic catalysis...
