-
Vismodegib, sold
under the
brand name Erivedge, is a
medication used for the
treatment of basal-cell
carcinoma (BCC). The
approval of
vismodegib on January...
- by the FDA;
vismodegib in 2012, and
sonidegib in 2015.
Vismodegib was the
first Shh
pathway drug
approved for
treating cancer.
Vismodegib was designed...
-
Teniposide Tafluposide Bortezomib Erlotinib Gefitinib Imatinib Vemurafenib Vismodegib Azacitidine Azathioprine Capecitabine Cytarabine Doxifluridine Fluorouracil...
- Food and Drug
Administration (FDA) for
cancer treatment.
These include vismodegib and sonidegib, both
inhibitors of
Smoothened (SMO),
which are
being used...
- by chemotherapy.
These experimental procedures are not
standard care.
Vismodegib and
sonidegib are
drugs approved for
specially treating BCC, but are expensive...
- (midazolam), for
insomnia and
procedural sedation and analgesia.
Erivedge (
vismodegib), for basal-cell carcinoma.
Esbriet (pirfenidone), for
idiopathic pulmonary...
- YW,
Macdonald JB,
Nelson SA,
Sekulic A (December 2017). "Treatment of
vismodegib-****ociated
muscle cramps with cyclobenzaprine: A
retrospective review"...
- from
cyclopamine and
vismodegib.
Itraconazole (ITZ)
inhibits SMO in the
presence of
mutations conferring resistance to
vismodegib and
other cyclopamine-competitive...
-
target of the
natural teratogen cyclopamine. It also is the
target of
vismodegib, the
first hedgehog pathway inhibitor to be
approved by the U.S. Food...
-
treatments that can lead to
dysgeusia are cyclophosphamide, cisplatin,
vismodegib, and etoposide. The
exact mechanism of chemotherapy-induced dysgeusia...
