- A 70 kg man
contains around 120 g of creatine, with 40%
being the
unphosphorylated form and 60% as
creatine phosphate. Of that amount, 1–2% is broken...
- liver,
skeletal muscle, heart, brain, and kidneys. ThMP and free (
unphosphorylated)
thiamine are
present in plasma, milk,
cerebrospinal fluid, and, it...
- They are
regulated by Ca2+/calmodulin and
protein kinase C. In
their unphosphorylated form, they bind to
actin filaments,
causing them to crosslink, and...
- The
unphosphorylated moiety of fingolimod,
which is the
predominant form of the drug in the body, is also an
active molecule.
Unphosphorylated fingolimod...
-
inhibits (Na+ + K+)ATPase by
blocking a
conformational change of the
unphosphorylated form". Nature. 282 (5736): 333–335. Bibcode:1979Natur.282..333K. doi:10...
- of the CDK1
phosphatase CDC25B to keep it in the cytoplasm; in its
unphosphorylated form, CDC25B
migrates to the nucleus.
Protein kinase C (PKC) may also...
- c-Met ****umes an inactive,
unphosphorylated conformation with AM7,
which can bind to both
phosphorylated and
unphosphorylated conformations of the kinase...
- the cAMP-dependent
protein kinase (PKA) in
cardiac muscle. In the
unphosphorylated state,
phospholamban is an
inhibitor of
cardiac muscle sarcoplasmic...
- that upon
ligand dissociation the
receptor reverts to its
original unphosphorylated state before a new
ligand binds. This
model predicts that
maximum response...
- The
three states of pyruvate,
phosphate dikinase (
unphosphorylated, monophosphorylated, and diphosphorylated) as it
converts pyruvate to phosphoenolpyruvate...
