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Trifluoroacetic acid (TFA) is an
organofluorine compound with the
chemical formula CF3CO2H. It is a
haloacetic acid, with all
three of the
acetyl group's...
-
Trifluoroacetic anhydride (TFAA) is the acid
anhydride of
trifluoroacetic acid. It is the
perfluorinated derivative of
acetic anhydride. Trifluoroacetic...
- the
sodium salt of
trifluoroacetic acid. It is used as a
source of trifluoromethylations. With a pKa of 0.23 for
trifluoroacetic acid, the trifluoroacetate...
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trisubstituted alkene. In
another synthetic method Markovnikov addition of
trifluoroacetic acid
followed by
hydrolysis of the
acetate gives terpineol. The most...
- origin, and is
thought to
result from the
metabolism of
halothane to
trifluoroacetic acid via
oxidative reactions in the liver.
About 20% of
inhaled halothane...
- group, give
stronger acids (the pKa of
acetic acid is 4.76
whereas trifluoroacetic acid, with a
trifluoromethyl substituent, has a pKa of 0.23). Electron-donating...
-
later be
removed from the
amine using moderately strong acids (e.g.,
trifluoroacetic acid). Thus, Boc
serves as a
protective group, for
instance in solid...
-
group in
amino acids can be
accomplished with
strong acids such as
trifluoroacetic acid in dichloromethane, or with HCl in methanol. A
complication may...
- acid. An
alternative route starts from limonene:
Limonene reacts with
trifluoroacetic acid in a
Markovnikov addition to a
trifluoroacetate intermediate,...
-
class of per- and
polyfluoroalkyl substances. The
simplest example is
trifluoroacetic acid.
These compounds are
organofluorine analogues of
ordinary carboxylic...
