- however, to
implicitly exclude the
globus pallidus when
referring to
striatal structures. In primates, the
striatum is
divided into the
ventral striatum...
-
striatum is the
expressed target the loop is
referred to as the cortico-
striatal-thalamic-cortical loop. The two
major input structures of the
circuit are...
-
contain both D1-type and D2-type receptors, with approximately 40% of
striatal MSNs
expressing both DRD1 and DRD2 mRNA.
These mixed-type NAcc MSNs with...
- MSNs of the
direct pathway and D2-type MSNs of the
indirect pathway. Most
striatal MSNs
contain only D1-type or D2-type
dopamine receptors, but a subpo****tion...
- Yes No Yes
Altered striatal dopamine signaling ↓DRD2, ↑DRD3 ↑DRD1, ↓DRD2, ↑DRD3 ↑DRD1, ↓DRD2, ↑DRD3 ↑DRD2 ↑DRD2
Altered striatal opioid signaling No...
- By
targeting A1-A2A
receptor heteromers in
striatal glutamatergic terminals and A1
receptors in
striatal dopaminergic terminals (presynaptic brake),...
-
Protein tyrosine phosphatase (PTP), non-receptor type 5, also
known as STEP (
STriatal-Enriched
protein tyrosine Phosphatase), was the
first brain-specific PTP...
-
number of motor-related areas. The
substantia nigra is the
source of the
striatal input of the
neurotransmitter dopamine,
which plays an
important role in...
-
Pennsylvania Children 2
Scientific career Fields Neurology Institutions Vanderbilt University Thesis Striatal vulnerability to
mitochondrial inhibition (1998)...
-
broad cognitive deficits.
Research is
inconclusive on age-related loss of
striatal dopamine transporter (DAT) sites,
suggesting cocaine has neuroprotective...