- In
molecular biology, a
scissile bond is a
covalent chemical bond that can be
broken by an enzyme.
Examples would be the
cleaved bond in the self-cleaving...
- is able to act as a nucleophile,
attacking the
carbonyl carbon of the
scissile peptide bond of the substrate. A pair of
electrons on the
histidine nitrogen...
- residues, and can
polarize the
glutamic acid's
oxygen atom,
proximate the
scissile bond, and
induce it to act as
reversible electron donor. This
forms an...
-
sides of the
unique palindromic nucleotide sequence AGATCT,
cleaving the
scissile phosphodiester bond
between the
first Adenine and
Guanine nucleotides on...
-
active site
residues to
activate a
water molecule,
which then
attacks the
scissile bond. A
seventh catalytic type of
proteolytic enzymes,
asparagine peptide...
-
peptide amide bonds where the side
chain of the
amino acid N-terminal to the
scissile amide bond (the P1 position) is a
large hydrophobic amino acid (tyrosine...
- to form a
covalent 3’-phosphotyrosine
linkage to the DNA substrate. The
scissile phosphate (phosphate
targeted for
nucleophilic attack at the
cleavage site)...
- in an α2-macroglobulin molecule, or a
homologous protein, that
contains scissile peptide bonds for
those proteinases that it inhibits) and a
thiol ester...
-
perform a
nucleophilic attack on the
carbonyl carbon of the
substrate scissile bond,
generating a
tetrahedral oxyanion intermediate stabilized by hydrogen-bonding...
-
alkaline cleavage of RNA. The
reaction is
therefore reversible, as the
scissile phosphate remains a phosphodiester, and may thus act as a
substrate for...
