- in the liver.
Parent non-toxic
chemicals are
generally referred to as
protoxins.
While toxication is
generally undesirable, in
certain cases it is required...
-
Protoxin-I, also
known as ProTx-I, or Beta/omega-theraphotoxin-Tp1a, is a 35-amino-acid
peptide neurotoxin extracted from the
venom of the
tarantula Thrixopelma...
-
research focus has been on the
design and
characterization of
prodrugs and
protoxins targeted for
activation by
cancer specific proteases. This
research is...
-
Protoxin-II, also
known as ProTx-II, PT-II or β/ω-TRTX-Tp2a, is a
neurotoxin that
inhibits certain voltage-gated
calcium and voltage-gated
sodium channels...
-
margins 'Violaceum' –
younger shoots and
branches have
bluish color A
protoxin present in the
seeds of Acer negundo, hypoglycin A, has been identified...
-
prodrugs are
converted into
their active metabolites, or the
toxication of
protoxins into
actual toxins. An
enzyme may be
reversibly or
irreversibly bioactivated...
-
substances are
bioactivated by CYP3A4 to form
their active compounds, and many
protoxins are
toxicated into
their toxic forms (see
table below for examples). CYP3A4...
- Once
ingested by the insect, the
dissolution of the
crystal allows the
protoxin to be released. The
toxin is then
activated by the
insect gut juice, and...
- A is
biosynthesized as a
pyrophosphate containing phosphocalyculin A
protoxins by a
hybrid PKS-NRPS
pathway within the
sponge bacterial symbiont, "Candidatus...
- viridochromogenes. It is also
known by the ISO
common name bilanafos.
Bialaphos is a
protoxin and
nontoxic as is. When it is
metabolized by a plant, the
glutamic acid...
