Definition of Picrotoxin. Meaning of Picrotoxin. Synonyms of Picrotoxin
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Definition of Picrotoxin
Picrotoxin Pic`ro*tox"in, n. [Gr. ? bitter + toxic + -in.]
A bitter white crystalline substance found in the cocculus
indicus. It is a peculiar poisonous neurotic and intoxicant,
and consists of a mixture of several neutral substances.
Meaning of Picrotoxin from wikipedia
, also known
as cocculin, is a poisonous crystalline plant
compound. It was first isolated
by the French pharmacist
and chemist Pierre
K, Wang SC. Respiratory stimulant effects
Therapeutics. 1975 May;193(2):657-63...
- family Cocculus
indicus, the fruit
cocculus, a source
, a poisonous alkaloid
with stimulant properties Cynosurus
indicus, a gr****...
toxin, an inhibitor
of G-protein coupled receptors Picrotoxin
, a poisonous crystalline plant alkaloid
Pneumothorax, a medical
- causing lethal
convulsions. Its effect
to but stronger
, a GABA-A receptor antagonist widely
used in research. As one of the most...
- convulsant potency
was strongly correlated
to in vitro affinity
to the picrotoxin binding
site on the GABA-A receptor
complex. Many GABA-A ligands
- Selective Brucine Strychnine Tutin
Non-selective Bicuculline Caffeine Picrotoxin Pitrazepin Thiocolchicoside Glycine receptor agonist
- by IUPHAR
as a major criterion
in the definition
Manske, R. H. F. (1932). "The Alkaloids
by GABAA antagonists
and by the glycine antagonist
strychnine, respectively. Mg2+ and DL-AP5...
SM, Frye CA (March 2005). "In the ventral tegmental
area picrotoxin blocks
FGIN 1-27-induced increases
in ****ual behavior
of rats and hamsters"...
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