- The
GABAA receptor (
GABAAR) is an
ionotropic receptor and ligand-gated ion channel. Its
endogenous ligand is γ-aminobutyric acid (GABA), the
major inhibitory...
-
receptors (
GABAAR). A
structural isomer of chloralose, β-chloralose (also
called parachloralose in
older literature), is
inactive as a
GABAAR modulator...
-
downstream sedative effects via
allosteric modulation and
agonism of
several GABAAR subtypes.
Similar to
other GABAergic agents,
methaqualone will
produce tolerance...
- In pharmacology,
GABAA receptor positive allosteric modulators, also
known as
GABAkines or
GABAA receptor potentiators, are
positive allosteric modulator...
-
Aguayo LG (2016). "Potentiation of
Gamma Aminobutyric Acid
Receptors (
GABAAR) by Ethanol: How Are
Inhibitory Receptors Affected?".
Frontiers in Cellular...
-
Himat Kumharo. Abrepota, Bakeja, Bahawalani, Damro, Damhio, Dandio, Gābar,
Gābaar, Gābhar, Gābrio, Gaad, Gohata, Gandhai, Husrani, Tayuja, Tar'ra, Tanak,...
- (2009). "Activity-dependent
tuning of
inhibitory neurotransmission based on
GABAAR diffusion dynamics". Neuron. 62 (5): 670–82. doi:10.1016/j.neuron.2009.04...
-
Carisoprodol allosterically modulates and
directly activates the
human α1β2γ2
GABAAR (GABAA) in the
central nervous system,
similar to barbiturates. This causes...
-
inactivation of
anesthesia inducing pot****ium
channels and the
localization of
GABAAR in synapses.
Anesthetics compete with
palmitate in
ordered lipids and this...
-
transmembrane four-α-helix
bundles of Cys-loop receptors. The
GABAA receptor (
GABAAR) is an
ionotropic receptor activated by the
inhibitory neurotransmitter...
