- can act as
nucleophiles.
Because nucleophiles donate electrons, they are
Lewis bases.
Nucleophilic describes the
affinity of a
nucleophile to bond with...
-
mechanism that is
common in
organic chemistry. In the SN2 reaction, a
strong nucleophile forms a new bond to an sp3-hybridised
carbon atom via a
backside attack...
-
chemical reactions in
which an electron-rich
chemical species (known as a
nucleophile)
replaces a
functional group within another electron-deficient molecule...
- and zero-order
dependence on the
nucleophile. This
relationship holds for
situations where the
amount of
nucleophile is much
greater than that of the...
- to make a
nucleophile is by a
catalytic triad,
where a
histidine residue is used to
activate serine, cysteine, or
threonine as a
nucleophile. This is not...
- From the
biological perspective, the key
reactions involve addition of
nucleophiles to the
formyl carbon in the
formation of
imines (oxidative deamination)...
-
addition is a
reaction between a
Michael donor (an
enolate or
other nucleophile) and a
Michael acceptor (usually an α,β-unsaturated carbonyl) to produce...
- amidases, esterases, acylases,
lipases and β-lactamases). An acid-base-
nucleophile triad is a
common motif for
generating a
nucleophilic residue for covalent...
- substitution, elimination, and
solvation reactions in
which water is the
nucleophile.
Biological hydrolysis is the
cleavage of
biomolecules where a water...
-
class of
substitution reactions involving nucleophiles and acyl compounds. In this type of reaction, a
nucleophile – such as an alcohol, amine, or enolate...