-
thyroid disease, and obesity.
Endocrine disease is
characterized by
misregulated hormone release (a
productive pituitary adenoma),
inappropriate response...
- and cell survival. As such, many
different types of
human tumors have
misregulated NF-κB: that is, NF-κB is
constitutively active.
Active NF-κB
turns on...
- PMID 21911480.
Trimborn M,
Schindler D,
Neitzel H,
Hirano T (2006). "
Misregulated chromosome condensation in MCPH1
primary microcephaly is
mediated by...
- muscle-specific
chloride channel in type 1
myotonic dystrophy due to
misregulated alternative splicing".
Molecular Cell. 10 (1): 45–53. doi:10.1016/s1097-2765(02)00572-5...
-
being investigated as a
method of
correcting the
expression levels of
misregulated genes in
neurodegenerative diseases.
Neurodengenerative diseases of motor...
- disease. Many
cancers arise from the
inappropriate epigenetic effects of
misregulated methylation. However,
because these processes are at
times reversible...
-
locally concentrate intrinsically disordered regions,
which in turn
misregulate Wnt signalling. Many
other large IDPs (Intrinsically
Disordered Proteins)...
-
regulate synaptic activity and how
these molecules and
organelles are
misregulated in Parkinson's disease. This has led to the
discovery of
specific presynaptic...
- et al. (February 2017). "Small
genomic insertions form
enhancers that
misregulate oncogenes".
Nature Communications. 8: 14385. Bibcode:2017NatCo...814385A...
-
obesity and diabetes. The
initial ****umption was that this
mutation was
misregulating FTO to
cause the
disease risk. However, it was
later shown that the...
