-
Allegood JC, Wang E,
Merrill AH Jr,
Schwartz GK (2009). "Safingol (L-threo-
sphinganine)
induces autophagy in
solid tumor cells through inhibition of PKC and...
-
Chemotherapeutic agents Fas
ligand Endotoxin Homocysteine Heat
Hydroxypalmitoyl Sphinganine Gamma interferon Ionizing radiation Matrix metalloproteinases Niacinamide...
-
Dehydrosphingosine is then
reduced by
NADPH to
dihydrosphingosine (
sphinganine),
acylated to
dihydroceramide finally oxidized by FAD to ceramide. Sphingosine...
- The
enzyme sphinganine-1-phosphate
aldolase (EC 4.1.2.27)
catalyzes the
chemical reaction sphinganine 1-phosphate ⇌ {\displaystyle \rightleftharpoons }...
-
forming 3-ketosphinganine (Fig. 1). This
product is then
reduced to
sphinganine, also
known as
dihydrosphingosine (dihydro-Sph; 2-amino-1,3-dihydroxy-octadecane)...
-
Sphinganine C4-monooxygenase (EC 1.14.13.169,
sphingolipid C4-hydroxylase, SUR2 (gene), SBH1 (gene), SBH2 (gene)) is an
enzyme with
systematic name sphinganine...
-
specifically known as
phytosphingosine and
dihydrosphingosine (also
known as
sphinganine,
although this term is less common), are
mainly C18 compounds, with somewhat...
- and
their Liseola section. They have
strong structural similarity to
sphinganine, the
backbone precursor of sphingolipids. More specifically, it can refer...
-
sphinganine,
sphingosine and
their 1-phosphate
metabolites and in
decreased concentrations of
complex sphingolipids. The ac****ulation of
sphinganine and...
- 3-dehydro-D-
sphinganine + CO2 Thus, the two
substrates of this
enzyme are palmitoyl-CoA and L-serine,
whereas its 3
products are CoA, 3-dehydro-D-
sphinganine, and...
