- mammals. These
compounds, specifically known
as sphinganine, although
this term is less common), are...
- been implicated
in autophagic induction
and ROS production. DL-threo-Dihydrosphingosine
at Sigma-Aldrich Schwartz, G. K., Haimovitz-Friedman, A., Dhupar,...
- rate-limiting step of the pathway. In turn, 3-keto-dihydrosphingosine
is then followed
by the enzyme...
- dehydrosphingosine. Dehydrosphingosine
is then reduced
(sphinganine), and finally oxidized
by FAD to sphingosine. There
of ketonic intermediates
in the synthesis
by cell-free extracts
ciferri". J. Biol. Chem. 244 (2):...
- palmitoyltransferase. The product
of this reaction
is reduced, yielding dihydrosphingosine
. The dihydrosphingosine undergoes
is the presence
(mainly 2′hydroxymyristol dihydrosphingosine
1-glucuronic acid, "SGL-1") in the outer membrane
of the cell wall...
- (February 2009). "FTY720 inhibits ceramide synthases
and up-regulates dihydrosphingosine
cells". The Journal...
- S1P: Palmitoyl-CoA Serine
3-Ketosphinganine (dehydrosphingosine) Dihydrosphingosine
(sphinganine) Dihydroceramide Ceramide Sphingosine
See also: Receptor/signaling...
- (phosphoethanolamine-forming). Other names
use include dihydrosphingosine
1-phosphate aldolase, sphinganine-1-phosphate alkanal-lyase, sphinganine-1-phosphate...