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Sialyl LewisX (sLeX), also
known as
cluster of
differentiation 15s (CD15s) or stage-specific
embryonic antigen 1 (SSEA-1), is a
tetrasaccharide carbohydrate...
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Carbohydrate antigen 19-9 (CA19-9), also
known as
sialyl-LewisA, is a
tetrasaccharide which is
usually attached to O-glycans on the
surface of cells. It...
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Metastatic breast cancer, also
referred to as metastases,
advanced breast cancer,
secondary tumors,
secondaries or
stage IV
breast cancer, is a
stage of...
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Sialyltransferases are
enzymes that
transfer sialic acid to
nascent oligosaccharide. Each
sialyltransferase is
specific for a
particular sugar substrate...
- organism. SabA (coded for by the sabA gene)
binds to
increased levels of
sialyl-Lewis X
antigen expressed on
gastric mucosa. The
outer membrane contains...
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leukocyte adhesion deficiency attributable to the
absence of
neutrophil sialyl-LewisX, a
ligand of P- and E-selectin on
vascular endothelium. It is ****ociated...
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cells and
interact with T
cells as part of the
adaptive immune response.
sialyl Lewis X
antigen on the
surface of leukocytes. H
antigen of the ABO blood...
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disaccharide antigen: the Thomsen-Friedenreich
antigen (Gal(b1-3)GalNAc). The
sialyl Tn
antigen (STn antigen) is
formed by
elongation with
sialic acid (Neu5Ac(α2-6)GalNAc)...
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combination of
sugar and protein.
These proteins often contain one or more
sialyl oligosaccharides that are
covalently bound to the rest of the molecule....
- to bind to
inward sialyl Lewis molecules ****her up
along the PSGL-1 chain,
increasing overall binding affinity—if the selectin-
sialyl Lewis bond breaks...
