Definition of Secretase. Meaning of Secretase. Synonyms of Secretase

Here you will find one or more explanations in English for the word Secretase. Also in the bottom left of the page several parts of wikipedia pages related to the word Secretase and, of course, Secretase synonyms and on the right images related to the word Secretase.

Definition of Secretase

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Meaning of Secretase from wikipedia

- Gamma secretase is a multi-subunit protease complex, itself an integral membrane protein, that cleaves single-p**** transmembrane proteins at residues...
- Beta-secretase 1, also known as beta-site amyloid precursor protein cleaving enzyme 1, beta-site APP cleaving enzyme 1 (BACE1), membrane-****ociated aspartic...
- processed by beta secretase and gamma secretase. The alpha-secretase pathway is the predominant APP processing pathway. Thus, alpha-secretase cleavage precludes...
- Beta-secretase 2 (EC 3.4.23.45, also known as Memapsin-1) is an enzyme that cleaves Glu-Val-Asn-Leu!Asp-Ala-Glu-Phe in the Swedish variant of Alzheimer's...
- Secretases are enzymes that "snip" pieces off a longer protein that is embedded in the cell membrane. Among other roles in the cell, secretases act on...
- Beta-secretase is a protein family that includes in humans Beta-secretase 1 and Beta-secretase 2. Tallon C, Farah MH (October 2017). "Beta secretase activity...
- Protein pigeon homolog also known as gamma-secretase activating protein (GSAP) is a protein that in humans is encoded by the PION gene. The human PION...
- amyloid-beta precursor protein (APP), which is cleaved by beta secretase and gamma secretase to yield Aβ in a cholesterol-dependent process and substrate...
- APP is cleaved into smaller fragments by enzymes such as gamma secretase and beta secretase. One of these fragments gives rise to fibrils of amyloid beta...
- transmembrane proteins which constitute the catalytic subunits of the gamma-secretase intramembrane protease protein complex. They were first identified in...