-
Prosaposin, also
known as PSAP, is a
protein which in
humans is
encoded by the PSAP gene. This
highly conserved glycoprotein is a
precursor for 4 cleavage...
-
neuronal loss.
Optic atrophy was only
reported in 1
patient It’s
known that
Prosaposin is a
precursor of a
Saposin A,B,C,D.
Saposin A is
needed to
activate galactocerbroside...
- cases, it may be
caused by a lack of
active saposin A (a
derivative of
prosaposin). The
buildup of
unmetabolized lipids adversely affects the
growth of...
- All
mammalian saposins are
synthesized as a
single precursor molecule (
prosaposin)
which contains four Saposin-B domains,
yielding the
active saposins after...
- LAMP2, GNS/N-acetylglucosamine-6-sulfatase, TSPAN6/tetraspanin-6, PSAP/
prosaposin, and TMEM192/transmembrane
protein 192 may
contribute to the execution...
- angiogenesis. Moreover,
stimulating TSP1 via over-expressing
prosaposin or
treating with a
small prosaposin-derived
peptide potently inhibits and even
induces regression...
-
protein Protein phosphatase with ef-hand
domain 2 PSAPL1:
encoding protein Prosaposin-like 1 (gene/pseudogene) QDPR:
quinoid dihydropteridine reductase RBM47:...
-
infantile Tay–Sachs
Metachromatic leukodystrophy (MLD)
Arylsulfatase A or
prosaposin Sulfatide compounds in
neural tissue Demyelination in CNS and PNS: Mental...
- that the PSI is the
first known example of an “enzyme
within an enzyme”.
Prosaposin Fusion protein Bryksa BC,
Bhaumik P,
Magracheva E, De
Moura DC, Kurylowicz...
- to
interact with HSPA1A and
Parkin (ligase). GPR37 is a
receptor for
prosaposin. It was
previously thought to be a
receptor for head activator, a neuropeptide...
