- In
clinical terms, a
potentiator is a
reagent that
enhances sensitization of an antigen.
Potentiators are used in the
clinical laboratory for performing...
-
positive allosteric modulators, also
known as
GABAkines or
GABAA receptor potentiators, are
positive allosteric modulator (PAM)
molecules that
increase the...
-
Gleason S,
Hayes KA, et al. (2020). "Efficacy and
Safety of the CFTR
Potentiator Icenticaftor (QBW251) in COPD:
Results from a
Phase 2
Randomized Trial"...
-
dysregulated in
cystic fibrosis.
Ivacaftor is a
selective small-molecule
potentiator of the CFTR
protein that
increases the protein's
ability to open chloride...
- "Pharmacological
detection of AMPA
receptor heterogeneity by use of two
allosteric potentiators in rat
hippocampal cultures".
British Journal of Pharmacology. 123 (7):...
- as
potentiators. RBCs have a net
negative charge called zeta
potential which causes them to have a
natural repulsion for one another.
Potentiators reduce...
-
protein cannot transport chloride through the channel. Ivacaftor, a CFTR
potentiator,
improves the
transport of
chloride through the ion
channel by binding...
-
severely dehydrated in pregnancy. An off-label use is as an opioid/opiate
potentiator. The drug
Diconal is a
combination of
cyclizine and the
opioid dipipanone...
-
itches and irritations, an antiemetic, as a weak analgesic, an
opioid potentiator, and as an
anxiolytic Vyvanse (lisdexamfetamine) – a pro-drug stimulant...
- (ErbB) FGF HGF (c-Met) Agonists:
Fosgonimeton Hepatocyte growth factor Potentiators:
Dihexa (PNB-0408)
Kinase inhibitors:
Altiratinib AM7 AMG-458 Amuvatinib...
