Definition of Oncogene. Meaning of Oncogene. Synonyms of Oncogene

- An oncogene is a gene that has the potential to cause cancer. In tumor cells, these genes are often mutated, or expressed at high levels. Most normal cells...
- Oncogene addiction is a process in which cancers with genetic, epigenetic, or chromosomal irregularities become dependent on one or several genes for maintenance...
- The RET proto-oncogene encodes a receptor tyrosine kinase for members of the glial cell line-derived neurotrophic factor (GDNF) family of extracellular...
- Oncogene is a peer-reviewed scientific journal published under the Springer Nature addressing cancer cell genetics and the structure and function of oncogenes...
- A tumor suppressor gene (TSG), or anti-oncogene, is a gene that regulates a cell during cell division and replication. If the cell grows uncontrollably...
- produce a functional fusion protein. Many important cancer-promoting oncogenes are fusion genes produced in this way. Examples include: Gag-onc fusion...
- into the host cell or to enhance already existing oncogenic genes (proto-oncogenes) in the genome. For example, it has been shown that vFLIP and vCyclin...
- cause AIDS. Duesberg received acclaim early in his career for research on oncogenes and cancer. With Peter K. Vogt, he reported in 1970 that a cancer-causing...
- positive regulator of cell migration. Akt1 was originally identified as the oncogene in the transforming retrovirus, AKT8. Akt2 is an important signaling molecule...
- to specificity of downstream signaling. It has been shown that the sis oncogene is derived from the PDGF B-chain gene. PDGF-BB is the highest-affinity...