- attack.
Neoantigens are
those that are
entirely absent from the
normal human genome. As
compared with
nonmutated self-proteins,
neoantigens are of relevance...
-
individualised neoantigen-specific
immunotherapy containing multiple different mRNA
species that
together encode up to 20
neoantigens that have been identified...
- mutations.
These mutations potentially create new
targetable antigens (
neoantigens) for use in T-cell immunotherapy. The
presence of CD8+ T
cells in cancer...
- an
epitope on a
neoantigen,
which is a
newly formed antigen that has not been
previously recognized by the
immune system.
Neoantigens are
often ****ociated...
-
Tumor antigen is an
antigenic substance produced in
tumor cells, i.e., it
triggers an
immune response in the host.
Tumor antigens are
useful tumor markers...
- peptides. A
requirement for the
recognition of
neoantigens by the
immune system is that the
neoantigens and
their antigenic determinants, the neoepitopes...
-
estimator of
neoantigen load and can help find the
patients who can
benefit from ICI
therapy by
increasing the
chance of
detecting the
neoantigens. However...
-
transposable elements, cell type (deconvolution) and the
presence of
neoantigens.
Prior to RNA-Seq, gene
expression studies were done with hybridization-based...
-
pattern of tumor-specific
mutated peptides referred to as
neoantigens or m-peptides.
Neoantigens are
products of
mutations that
first occur in the course...
-
Milighetti M,
Ceglia N,
Patterson E, et al. (19
February 2025). "RNA
neoantigen vaccines prime long-lived CD8+ T
cells in
pancreatic cancer". Nature:...
