-
Mycolactone is a polyketide-derived
macrolide produced and
secreted by a
group of very
closely related pathogenic mycobacteria species including M. ulcerans...
-
involved in the
production of the
toxin mycolactone.
Other closely related mycobacteria produce mycolactone and
infect various aquatic animals; these...
- open wounds. Once in the skin, M.
ulcerans grows and
releases the
toxin mycolactone,
which blocks the
normal function of cells,
resulting in
tissue death...
- ****ociation, a
former British trade union MLSA1 and MLSA2,
genes required for
mycolactone biosynthesis Multilocus sequence analysis, a
molecular biology technique...
-
cause tuberculosis and leprosy.
Mycobacterium ulcerans produces a toxin,
mycolactone, that
destroys tissue. The
prevalence of
Buruli ulcer is unknown. The...
-
produced by
bacteria have been
isolated and characterized, such as the
mycolactones. The
primary means of
bacterial resistance to
macrolides occurs by post-transcriptional...
-
accomplishments of his
research group include the
total syntheses of palytoxin,
mycolactones, halichondrins, saxitoxin, tetrodotoxin, geldanamycin, batrachotoxin...
