- are
usually 14-, 15-, or 16-membered.
Macrolides belong to the
polyketide class of
natural products. Some
macrolides have
antibiotic or
antifungal activity...
- is a
member of
macrolides that are a
class of
antibiotics with a
cyclic structure with a
lactone ring and
sugar moieties.
Macrolides can
inhibit CYP3A4...
-
resistance mechanism is only
induced by the
presence of 14-membered ring
macrolides, such as erythromycin.
During a D-test,
bacteria of the
iMLSB phenotype...
- In enzymology, a
macrolide 2'-kinase (EC 2.7.1.136) is an
enzyme that
catalyzes the
chemical reaction ATP +
oleandomycin ⇌{\displaystyle \rightleftharpoons...
-
Davidsen RB,
Feenstra B,
Krogh C, Diaz LJ, et al. (March 2014). "Use of
macrolides in
mother and
child and risk of
infantile hypertrophic pyloric stenosis:...
- recommended. In
those who are
allergic to penicillin,
cephalosporins or
macrolides may be used. In
children with
frequent episodes of tonsillitis, tonsillectomy...
- a
class of
macrolide antibiotics that were
originally manufactured in
response to the poor acid
stability exhibited by
original macrolides (erythromycin)...
-
interfering with the
synthesis of proteins. In a
mechanism similar to
macrolides and
streptogramin B,
lincosamides bind
close to the
peptidyl transferase...
- clarithromycin, or
azithromycin are
typically the
recommended treatment.
Newer macrolides are
frequently recommended due to
lower rates of side effects....
-
Clarithromycin should not be
taken by
people who are
allergic to
other macrolides or
inactive ingredients in the tablets,
including microcrystalline cellulose...