Definition of Mitofusins. Meaning of Mitofusins. Synonyms of Mitofusins

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Definition of Mitofusins

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Meaning of Mitofusins from wikipedia

- membrane fusion complex, Mitofusin 1 (Mfn1)/Mfn2/Optical Atrophy Protein 1 (OPA1) complex. This subfamily includes mitofusins 1 and 2. Mfn1 and Mfn2 (TC#...
- Mitofusin-2 is a protein that in humans is encoded by the MFN2 gene. Mitofusins are GTPases embedded in the outer membrane of the mitochondria. In mammals...
- mitochondrial-resident mitofusins form heterocomplexes that regulate the number of inter-organelle contact sites, although mitofusins were first identified...
- mitochondrial transport in the pathogenesis of Charcot-Marie-Tooth disease from mitofusin 2 mutations". The Journal of Neuroscience. 27 (2): 422–430. doi:10.1523/JNEUROSCI...
- level of the outer mitochondrial membrane is mediated by Mfn1 and Mfn2 (Mitofusins 1 and 2), and fusion at the level of the inner mitochondrial membrane...
- includes classical dynamins, dynamin-like proteins, Mx proteins, OPA1, mitofusins, and GBPs. Members of the dynamin family are prin****lly involved in the...
- D, Lombès A (2003). "Membrane topology and mitochondrial targeting of mitofusins, ubiquitous mammalian homologs of the transmembrane GTPase Fzo". J. Cell...
- ubiquitination in a self-reinforcing cycle. Parkin substrates include mitofusins Mfn1 and Mfn2, which are large GTPases that promote mitochondria fusion...
- MIB2 (1p36) MIER1 (1p31) MIGA1: encoding protein Mitoguardin 1 MFN2: mitofusin 2 MFSD2: Major facilitator superfamily domain containing 2A MIR6079: microRNA...
- UCP; nuclear factor erythroid 2 like 2, NFE2L2) and a dynamics gene (mitofusin 1, MFN1) were upregulated (P < 0.05) at a low dose of NPY, while a high...