-
Mitofusin-2 is a
protein that in
humans is
encoded by the MFN2 gene.
Mitofusins are
GTPases embedded in the
outer membrane of the mitochondria. In mammals...
- also
control mitochondrial fission.
These groups of
proteins include mitofusins, OPA1/Mgm1, and Drp1/Dnm1. All of
these molecules are GTP hydrolyzing...
- ganglioside-induced differentiation-****ociated
protein 1 (GDAP1), and
mitofusin 2 (MFN2), can
cause axonal forms of CMT. Due to the
close interaction...
-
Mitofusin-1 is a
protein that in
humans is
encoded by the MFN1 gene. The
protein encoded by this gene is a
mediator of
mitochondrial fusion. This protein...
- mitochondrial-resident
mitofusins form
heterocomplexes that
regulate the
number of inter-organelle
contact sites,
although mitofusins were
first identified...
- to an
identified protein substrate. MARCH5 was
firstly identified as a
mitofusin 2- and Drp1-binding protein. MARCH5
promotes ubiquitination of Drp1 and...
- UCP;
nuclear factor erythroid 2 like 2, NFE2L2) and a
dynamics gene (
mitofusin 1, MFN1) were
upregulated (P < 0.05) at a low dose of NPY,
while a high...
-
protein superfamily includes classical dynamins, GBPs, Mx proteins, OPA1,
mitofusins in Eukaryote, and
bacterial dynamin-like
proteins (BDLPs) in Prokaryote...
- MIB2 (1p36) MIER1 (1p31) MIGA1:
encoding protein Mitoguardin 1 MFN2:
mitofusin 2 MFSD2:
Major facilitator superfamily domain containing 2A MIR6079: microRNA...
- with
mitofusin.
According to one model,
damaged mitochondria are
sequestered from
healthy mitochondria by the
degradation of Miro and
mitofusin. Miro...
