-
Bigam G, Chan KJ (1985). "Biosynthesis of the
hypocholesterolemic agent mevinolin by
Aspergillus terreus.
Determination of the
origin of carbon, hydrogen...
- 1016/B978-008045382-8.00017-4. ISBN 9780080453828.
Lovastatin (also
known as
mevinolin) is
produced by
Aspergillus terreus Gent,
Janneane F; Ren, Ping; Belanger...
- to
produce aspulvinone, asterriquinone, butyrolactones, citreoviridin,
mevinolin, terrain, and
terrequinone A. A. neoafric**** has been
cultivated on both...
-
trips to ****an
starting in 1975. By 1978,
Merck had
isolated lovastatin (
mevinolin, MK803) from the
fungus Aspergillus terreus,
first marketed in 1987 as...
-
trips to ****an
starting in 1975. By 1978,
Merck had
isolated lovastatin (
mevinolin, MK803) from the
fungus Aspergillus terreus,
first marketed in 1987 as...
- as enzymes, like xylanase. It was also the
initial source for the drug
mevinolin (lovastatin), a drug for
lowering serum cholesterol.
Aspergillus terreus...
- "Synthesis of a
chiral synthon for the
lactone portion of
compactin and
mevinolin".
Tetrahedron Lett. 29 (11): 1255–8. doi:10.1016/s0040-4039(00)80269-5...
-
alabamensis producing the
mycotoxins citrinin and
citreoviridin but
lacking mevinolin.
Aspergillus alabamensis was
discovered by
Balajee and
colleagues in 2009...
-
their product showed good HMGR
inhibition and they
named the
product mevinolin,
which later became known as lovastatin. The
cholesterol controversy began...
-
their degradation studies of the cholesterol-lowering
fungal metabolite mevinolin. This
interesting sequence features the
addition of
excess n-butyllithium...
