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Mevastatin (
compactin, ML-236B) is a
hypolipidemic agent that
belongs to the
statins class. It was
isolated from the mold
Penicillium citrinum by Akira...
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subsequent G1-phase arrest, as seen in
cells of
different cancer lines.
Compactin and lovastatin,
natural products with a
powerful inhibitory effect on...
- hours.
Initially known as CS-514,
pravastatin is a
derivative of ML236B (
compactin),
which was
identified in a
fungus called Penicillium citrinum in the...
-
isolated the same
compound from
Penicillium brevicompactum,
named it
compactin, and
published their report in 1976. The
British group mentions antifungal...
- been used in
antibiotics such as patulin,
cholesterol medication such as
compactin, and
antifungal treatments. It has also been
reported that polyketides...
- 1hw8:
COMPLEX OF THE
CATALYTIC PORTION OF
HUMAN HMG-COA
REDUCTASE WITH
COMPACTIN (ALSO
KNOWN AS MEVASTATIN) 1hw9:
COMPLEX OF THE
CATALYTIC PORTION OF HUMAN...
-
occur in
their hydroxyl acid forms,
along with
dehydroxymonacolin and
compactin (mevastatin). The
prescription drug Lovastatin,
identical to monacolin...
- It is
known to
produce various compounds including polygalacturonase,
compactin, cyclopenin, cyclopenol, cyclopeptin, dehydrocompactin, dihydrocyclopeptin...
- 1021/jo00172a070.
Masahiro Hirama,
Mitsuko Uei: "A
chiral total synthesis of
compactin", in: J. Am. Chem. Soc., 1982, 104, pp. 4251–4253; doi:10.1021/ja00379a037...
- for
physical and
mental health and for sociopolitics. 1976:
Mevastatin (
compactin; ML-236B) was
independently discovered by
Akira Endo in ****an in a culture...