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Maraviroc, sold
under the
brand names Selzentry (US) and
Celsentri (EU), is an
antiretroviral medication used to
treat HIV infection. It is
taken by mouth...
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accommodating both
endogenous chemokines and
small molecule inhibitors like
maraviroc, with key
residues such as Glu283 and Tyr251
mediating ligand interactions...
- and
Pfizer with
maraviroc.[citation needed] All of the
compounds reached clinical trials in humans;[citation needed] only
maraviroc has been approved[vague]...
- Vicriviroc,
similar to
maraviroc, is
currently undergoing clinical trials for FDA approval. Aplaviroc, an
agent similar to
maraviroc and vicriroc. Clinical...
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negative allosteric modulators (NAM)
lower agonist affinity and/or efficacy.
Maraviroc is a
medicine that
modulates CCR5. Fenobam,
raseglurant and dipraglurant...
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Letermovir (Prevymis)
Cytomegalovirus (CMV)
Lopinavir HIV
Loviride HIV
Maraviroc HIV
entry inhibitor Methisazone Smallpox Molnupiravir COVID-19
Merck &...
-
Stavudine (d4T)
Etravirine Fosamprenavir Indinavir Lamivudine (3TC)
Lopinavir Maraviroc Nelfinavir Nevirapine Raltegravir Ritonavir Saquinavir Tenofovir Tipranavir...
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blocking one of
several targets.
Maraviroc,
enfuvirtide and
Ibalizumab are
available agents in this class.
Maraviroc works by
targeting CCR5, a co-receptor...
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creating new
blood vessels in the body.
Another discovery made
using HTS is
Maraviroc. It is an HIV
entry inhibitor, and
slows the
process and
prevents HIV...
-
Lexiva and Telzir)
nelfinavir (brand name Viracept)
Entry inhibitors:
maraviroc (brand
names Selzentry and Celsentri)
Antiretroviral fixed-dose combinations...