- post-transcriptionally,
regulating mRNA
splicing and
transport to the cytoplasm. The
lentiviral proteome consists of five
major structural proteins and
three or four...
-
Lentiviral vectors in gene
therapy is a
method by
which genes can be inserted, modified, or
deleted in
organisms using lentiviruses.
Lentiviruses are a...
- For instance,
relatively non-immunogenic and
integrative vectors like
lentiviral vectors are
commonly emplo**** for gene therapy.
Chimeric viral vectors—such...
-
libraries created by the
Zhang lab.
Available through Addgene,
these lentiviral libraries respectively target human and
mouse exons, and both are available...
- used in
clinical trials for HIV and SARS-CoV-2, or
cancer vaccines.: 5
Lentiviral vectors based on lentivirus, a retrovirus, can
modify a cell's nuclear...
- (2006). "Nef-mediated
suppression of T cell
activation was lost in a
lentiviral lineage that gave rise to HIV-1". Cell. 125 (6): 1055–67. doi:10.1016/j...
- has been
engineered into a
viral vector for gene therapy. Like
other lentiviral vectors, FIV
vectors integrate into the
chromosome of the host cell, where...
-
anemia to
clinically asymptomatic individuals.
LentiGlobin BB305 is a
lentiviral vector which inserts a
functioning version of the HBB gene into a recipient's...
- Gene
therapy using lentiviral vectors was
being explored in
early stage trials as of 2009.[needs update] In a
Phase I
clinical trial of
three patients...
-
Jennifer M.; Cowan,
Morton J.; Sorrentino,
Brian P. (18
April 2019). "
Lentiviral Gene
Therapy Combined with Low-Dose
Busulfan in
Infants with SCID-X1"...
