-
strand (intrastrand) or
between opposite strands of double-stranded DNA (
interstrand).
These adducts interfere with
cellular metabolism, such as DNA replication...
- atom
forms the
second alkylation step that
results in the
formation of
interstrand cross-links (ICLs) as it was
shown in the
early 1960s. At that time,...
-
Marchetti F,
Bishop J,
Gingerich J,
Wyrobek AJ (2015-01-08). "Meiotic
interstrand DNA
damage escapes paternal repair and
causes chromosomal aberrations...
- PMID 17978187.
Marchetti F,
Bishop J,
Gingerich J,
Wyrobek AJ (2015). "Meiotic
interstrand DNA
damage escapes paternal repair and
causes chromosomal aberrations...
-
damaged sites, and its
recruitment is most
rapid and
robust as follows:
interstrand crosslinks > double-strand
breaks >
monoadducts >
oxidative damage. CSB...
-
colorectal cancers.
Colibactin is a
polyketide peptide that can form
interstrand crosslinks in DNA.
Colibactin is only
produced by
bacterial strains containing...
- Mason,
Tracey Mcgregor; Miller, Paul S. (2006). "Formation and
Repair of
Interstrand Cross-Links in DNA".
Chemical Reviews. 106 (2): 277–301. doi:10.1021/cr040478b...
-
treatment of
vitiligo and hand eczema.
After photoactivation it
creates interstrand cross-links in DNA,
which can
cause programmed cell
death unless repaired...
- β-chloro-nitrosourea compound. As an
alkylating agent,
carmustine can form
interstrand crosslinks in DNA,
which prevents DNA
replication and DNA transcription...
-
protein is a
protein that in
humans is
encoded by the DCLRE1A gene. DNA
interstrand cross-links
prevent strand separation,
thereby physically blocking transcription...
