- body
through urine or **** (via bile from the liver).
Hormones are
glucuronidated to
allow for
easier transport around the body.
Pharmacologists have...
-
Biotransformation is the
biochemical modification of one
chemical compound or a
mixture of
chemical compounds.
Biotransformations can be
conducted with...
- 11-nor-9-carboxy-THC (THC-COOH)
which is
inactive at the CB1 receptors; and
further glucuronidated to form 11-nor-Δ9-tetrahydrocannabinol-9-carboxylic acid glucuronide...
- 6α-oxycodol-N-oxide and 6β-oxycodol-N-oxide (which can
subsequently be
glucuronidated as well).
Oxymorphone is also
further metabolized, as follows: 3-Glucuronidation...
- half-life of
glucuronic acid substrates,
causing the
plasma levels of
glucuronidated drugs to fall
below their therapeutic threshold.
Excessive glucuronidation...
-
substance is
rapidly absorbed. It is
oxidised to a
carboxylic acid,
glucuronidated, and
quickly eliminated via the kidneys. AMC is a
derivative of m-cresol...
- catechol-O-methyltransferase. Four of the five
hydroxyl groups of
quercetin are
glucuronidated by UDP-glucuronosyltransferase. The
exception is the 5-hydroxyl group...
- formulations.[citation needed] It is
further converted to 3-HM by CYP3A4 or
glucuronidated.
Dextrorphan was
formerly a
Schedule I
controlled substance in the United...
-
hydroxylated derivatives. These, as well as the
original drug, are
further glucuronidated,
mainly by the
enzymes UGT1A1, 1A8, and 1A9.
Febuxostat and its metabolites...
- in humans.
Canrenone may be
further reduced (into di-, tetra-, and
hexahydrogenated metabolites), hydroxylated, and
conjugated (e.g.,
glucuronidated)....
