-
Fibrillin is a glycoprotein,
which is
essential for the
formation of
elastic fibers found in
connective tissue.
Fibrillin is
secreted into the extracellular...
-
Fibrillin-1 is a
protein that in
humans is
encoded by the FBN1 gene,
located on
chromosome 15. It is a large,
extracellular matrix glycoprotein that serves...
- variable. MFS is
caused by a
mutation in FBN1, one of the
genes that make
fibrillin,
which results in
abnormal connective tissue. It is an
autosomal dominant...
-
contractural arachnodactyly,
which is
caused by
mutation in the gene
encoding fibrillin-2 on
chromosome 5q23. It
remains unconfirmed whether composer Sergei Rachmaninoff's...
- as they move down from the
cells surface before being deposited onto
fibrillin microfibrillar scaffolds.
Following deposition onto
microfibrils tropoelastin...
-
unlike Marfan's, CCA is
caused by
mutations to the
fibrillin-2 (FBN2) gene
rather than the
fibrillin-1 (FBN1) gene.
Signs and
symptoms of CCA
often resemble...
- gene,
which encodes fibrillin-1.
Fibrillin-1 is an
extracellular matrix protein that is
found in microfibrils;
defects in the
fibrillin-1
protein cause the...
- cell
continues getting wrapped.
Fibrillin microfibrils are
found in
connective tissues,
which mainly makes up
fibrillin-1 and
provides elasticity. During...
- seen to have two
consequences for
protein production: a mutant/truncated
fibrillin protein and very low
plasma asprosin levels (from a
postulated dominant...
- purple/black with Verhoeff's stain. The
extracellular matrix contains Elastin,
fibrillin, glycoproteins,
collagen types II, IX, X, and XI, and the proteoglycan...
