- citalopram. Here, (S)-citalopram is
called a
chiral switch of Citalopram.
Enantiopure compounds consist of only one of the two enantiomers.
Enantiopurity is...
- An
enantiopure drug is a
pharmaceutical available in one
specific enantiomeric form. Most
biomolecules (proteins, sugars, etc.) are
present in only one...
- The
chiral pool is a "collection of
abundant enantiopure building blocks provided by nature" used in synthesis. In
other words, a
chiral pool
would be...
- "methamphetamine hydrochloride" may
suggest a
racemic mixture,
Desoxyn contains enantiopure dextromethamphetamine,
which is a more
potent stimulant than both levomethamphetamine...
-
analgesic action, it
possesses central analgesic action.
Chiral switch Enantiopure drug
Chirality "Medicinal
products authorised in Estonia".
State Agency...
- the
United States.
Methylphenidate was
introduced in the 1950s, and
enantiopure dextroamphetamine in the 1970s. The use of
stimulants to
treat ADHD was...
- Benzedrine, and also as an oral
tablet since 1938.
Dexamyl utilized its
enantiopure isomer of
greater central nervous system (CNS) selectivity, dextroamphetamine...
-
synthetic methodology was
introduced in 1997 by
Jonathan A.
Ellman et al.
Enantiopure tert-butanesulfinamide can be
prepared by
enantioselective oxidation...
-
active enantiomer,
arketamine (R-ketamine), has
never been
marketed as an
enantiopure drug for
clinical use.
While S-ketamine is more
effective as an analgesic...
- of that compound,
provided that the
specific rotation ([α]) for the
enantiopure compound is known. The
variance of
specific rotation with wavelength—a...
