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hERG (the
human Ether-à-go-go-Related Gene) is a gene (KCNH2) that
codes for a
protein known as Kv11.1, the
alpha subunit of a pot****ium ion channel. This...
- (born
August 6, 1979) is a
Nigerian Executive business leader,
founder of
EmHERging a
mentorship platform and
former chief executive officer of EKo Electricity...
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Quinidine ShK-186
Sotalol Tedisamil Terikalant Tetraethylammonium Vernakalant hERG (KCNH2, Kv11.1)-specific:
Ajmaline Amiodarone AmmTX3
Astemizole Azaspiracid...
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Retrieved 27
November 2011.
Adolph O, Köster S,
Georgieff M,
Georgieff EM,
Moulig W, Föhr KJ (August 2012). "Promethazine
inhibits NMDA-induced currents...
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antagonist of the D2, D3, and D4
receptors and the 5-HT7 receptor. It is also a
hERG blocker.
Similarly to
other typical antipsychotics pimozide has a high affinity...
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dopamine reuptake inhibitor) Nav1.7, Nav1.8, and Nav1.9
sodium channel blocker HERG pot****ium
channel blocker George Rieveschl was a
professor of
chemistry at...
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Muscarinic agonists: Xanomeline/trospium
chloride Others/unknown:
Azacyclonol #WHO-
EM ‡Withdrawn from
market Clinical trials: †Phase III §Never to
phase III...
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responsible for the drug's
efficacy against positive symptoms. D3 2.30 D4 4.92
hERG 3
Responsible for the QT
interval prolongation and
torsade de
pointes H1...
-
Suessbrich H,
Waldegger S, Lang F,
Busch AE (April 1996). "Blockade of
HERG channels expressed in
Xenopus oocytes by the
histamine receptor antagonists...
-
Quinidine ShK-186
Sotalol Tedisamil Terikalant Tetraethylammonium Vernakalant hERG (KCNH2, Kv11.1)-specific:
Ajmaline Amiodarone AmmTX3
Astemizole Azaspiracid...
