Definition of Bioisostere. Meaning of Bioisostere. Synonyms of Bioisostere

- In medicinal chemistry, bioisosteres are chemical substituents or groups with similar physical or chemical properties which produce broadly similar biological...
- compounds containing an isostere is called a bioisostere. This is frequently used in drug design: the bioisostere will still be recognized and accepted by...
- 1]propellane. The bicyclo[1.1.1]pentane structure has been used as an unusual bioisostere for a phenyl ring. Housane Wiberg, Kenneth B.; Walker, Frederick H. (1982)...
- the Dimroth rearrangement. 1,2,3-Triazole finds use in research as a bioisostere in medicinal chemistry building block for more complex chemical compounds...
- in place of one hydrogen atom at the C9α position. Fluorine is a good bioisostere for hydrogen because it is similar in size, with the major difference...
- same degree as in synthetic areas.) Chemistry portal Science portal Bioisostere Biological machines Chemoproteomics Drug design Pharmacognosy Pharmacokinetics...
- as alpha-methyldopamine, it was hoped that the difluoromethylenedioxy bioisostere would show increased metabolic stability and less toxicity. These compounds...
- a tetrazole which is being used in place of the carboxylic acid as a bioisostere. Losartan is used for hypertension, including in people with left ventricular...
- intense in the mid-1940s. The trifluoromethyl group is often used as a bioisostere to create derivatives by replacing a chloride or a methyl group. This...
- This is a list of cocaine analogues. A cocaine analogue is an (usually) artificial construct of a novel chemical compound from (often the starting point...