Definition of Isostere. Meaning of Isostere. Synonyms of Isostere

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Definition of Isostere

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Meaning of Isostere from wikipedia

- classical Isosteres are molecules or ions with similar shape and often electronic properties. Many definitions are available. but the term is usually...
- properties. Alloxanthine is an inhibitor of xanthine oxidase. It is also an isostere of xanthine, the normal substrate for the enzyme. Alloxanthine is considered...
- is a derivative of anthranilic acid,: 235  which in turn is a nitrogen isostere of salicylic acid, which is the active metabolite of aspirin.: 235  Several...
- compound can be classified as a cyclic amide, and as such is used as an isostere for peptides and other pharmaceutically inspired targets. The 4-methyl-2-quinolone...
- Non-canonical base pairs are planar hydrogen bonded pairs of nucleobases, having hydrogen bonding patterns which differ from the patterns observed in Watson-Crick...
- is a derivative of anthranilic acid,: 235  which in turn is a nitrogen isostere of salicylic acid, which is the active metabolite of aspirin.: 235 : 17 ...
- Quantitative Control of Dihydrofolate Reductase Activity by Using a Photochromic Isostere of an Inhibitor". ChemBioChem. 20 (11): 1382–1386. doi:10.1002/cbic.201800816...
- require hematological monitoring. Investigation on a series of thiophene isosteres on 1 of the phenyl rings in clozapine, a thienobenzodiazepine analog (olanzapine)...
- transport. Furthermore, their geometry and stability make them suitable isosteres for benzene rings. The classic 1964 synthesis starts with the conversion...
- acidic proton at the nitrogen. The tetrazole represents a non-classical bio-isostere. The carboxylate seen in the molecule is the active moiety after the molecule...