- "Cheminformatics
Analysis of
Organic Substituents:
Identification of the Most
Common Substituents,
Calculation of
Substituent Properties, and
Automatic Identification...
-
position of
substituents other than
hydrogen in
relation to each
other on an
aromatic hydrocarbon. In ortho-substitution, two
substituents occupy positions...
-
substituent or
substituents equatorial. When
multiple substituents are
taken into consideration, the
conformation where the
substituent with the largest...
- both
substituents are the same, some
general trends usually hold.
These trends can be
attributed to the fact that the
dipoles of the
substituents in a...
-
allowing the
substituent to bond to the more-stable
carbocation and the more-substituted carbon. Syn
addition is the
addition of two
substituents to the same...
- from
nearly zero for very
small substituents such as deuterium, to
about 5 kcal/mol (21 kJ/mol) for very
bulky substituents such as the tert-butyl group...
-
substituents.
Repeating the
process with meta-
substituents afford the meta
substituent constants. This
treatment does not
include ortho-
substituents,...
- When two
substituents are
already present on the ring, the
third substituent's new
location is
relatively predictable. If the
existing substituents reinforce...
-
relationship between the
orbital hybridization and the
electronegativities of
substituents. The rule was
stated by
Henry A. Bent as follows:
Atomic s character...
- Upon reacting,
substituents will be
added at the ortho, para or meta positions,
depending on the
directivity of the
current substituents to make more complex...
