-
Cancer Chemotherapeutic Agents: DNA-Interactive
Alkylating Agents and
Antitumour Platinum-Based Drugs". The
Cancer Handbook. John
Wiley & Sons, Ltd. doi:10...
- a
mitomycin that is used as a
chemotherapeutic agent by
virtue of its
antitumour activity. It is
given intravenously to
treat upper gastro-intestinal cancers...
-
extreme cytotoxicity and thus
represent a
class of
exceptionally potent antitumour antibiotics. As small-molecule, synthetic, DNA
minor groove binding alkylating...
-
Micromonospora lupini is an
endophytic actinomycete notable for
producing antitumour anthraquinones:
lupinacidins A (1), B (2) and C. Its
genome has been sequenced...
-
treatment of
small cell lung
cancer (SCLC). It has been seen to show
superior antitumour efficacy,
which is
purported to be
linked to the
activation of p53-independent...
-
Mitomycin C, an aziridine, is used as a
chemotherapeutic agent by
virtue of its
antitumour activity....
- T
helper cell
cytokines (such as Interferon-gamma) and
recruitment of
antitumour effector cells. Most
commonly histiocytomas are
found in
young dogs and...
-
exists as a
bright red
solid that
slowly hydrolyzes in air. It
shows antitumour activity and was the
first non-platinum
complex to
undergo clinical trials...
- have the
ability to make some cytokines, such as TNF-α and IFN-γ, with
antitumour and
antimicrobial effects. The
immune system must
recognize millions of...
- loss, and nephrotoxicity.)
Organoplatinum compounds such as the
above antitumour agents, as well as
soluble inorganic platinum complexes, are routinely...
