- biochemistry,
thioesterases are
enzymes which belong to the
esterase family. Esterases, in turn, are one type of the
several hydrolases known.
Thioesterases exhibit...
- Acyl-protein
thioesterases are
enzymes that
cleave off
lipid modifications on proteins,
located on the
sulfur atom of
cysteine residues linked via a thioester...
- Acyl-CoA
thioesterase 1 is a
protein that in
humans is
encoded by the ACOT1 gene. The ACOT1 gene is
located on the 14th chromosome, with its
specific localization...
-
Palmitoyl protein thioesterase,
enzymes that
remove thioester-linked
fatty acyl
groups PPT1, a
member of the
palmitoyl protein thioesterase family PPT2, a...
- Acyl-CoA
thioesterase 9 is a
protein that is
encoded by the
human ACOT9 gene. It is a
member of the acyl-CoA
thioesterase superfamily,
which is a group...
- Acyl-coenzyme A
thioesterase 8 is an
enzyme that in
humans is
encoded by the ACOT8 gene. The
protein encoded by this gene is a
peroxisomal thioesterase that appears...
-
synthesis of 9-HN (Figure 5). MmpB
contains a KS, KR, DH, 3 ACPs, and a
thioesterase (TE) domain. It does not
contain an
enoyl reductase (ER) domain, which...
- mode of
action avoids resistance. It
works by
inhibiting fatty acid
thioesterase,
disrupting cell membranes. It was
introduced in 1989. As of 2025, approval...
-
results in a
deficient form of a
lysosomal enzyme called palmitoyl protein thioesterase 1 (PPT1). The wild-type PPT1 is a 306-amino acid
polypeptide that is...
- of an acyl
carrier protein (ACP), and is
released by the
action of a
thioesterase (TE) upon
reaching a
carbon chain length of 16 (palmitic acid). There...
