-
Terfenadine is an
antihistamine formerly used for the
treatment of
allergic conditions. It was
brought to
market by
Hoechst Marion Roussel (now Sanofi)...
-
nonsedating antihistamine,
terfenadine (trade name Seldane), and, therefore, put
loratadine on a
lower priority. However,
terfenadine had to be
removed from...
- sulfanilamide.
Since that time, many
other examples have been identified.
Terfenadine, the
first non-sedating antihistamine, had to be
withdrawn from the market...
- (April 1999). "Affinities of brompheniramine, chlorpheniramine, and
terfenadine at the five
human muscarinic cholinergic receptor subtypes". Pharmacotherapy...
- group, and both
hydroxyl (-OH) groups. The
older antihistaminic agent terfenadine was
found to
metabolize into the
related carboxylic acid, fexofenadine...
- tranquilizer, was
developed in 1956. The
first non-sedating
antihistamine was
terfenadine (Seldane) and was
developed in 1973. Subsequently,
other non-sedating...
- hy****nsitivity to
other azole medicines such as ketoconazole; are
taking terfenadine, if 400 mg per day
multidose of
fluconazole is administered; concomitant...
- or
drugs that also
prolong the QT interval.
Other examples include terfenadine (Seldane, Seldane-D),
astemizole (Hismanal),
cisapride (Propulsid, withdrawn...
- is the
parent structure of the
antihistamines fexofenadine and
terfenadine.
Terfenadine produces azacyclonol as a
major active metabolite. It is made by...
- and absorbed, as in the case of the
histamine H1-receptor
antagonist terfenadine.
Recently CYP3A4 has also been
identified in the brain, but its role...
