-
Transthyretin (TTR or TBPA) is a
transport protein in the
plasma and
cerebrospinal fluid that
transports the
thyroid hormone thyroxine (T4) and retinol...
- dialysis-related (Aβ2M), and
hereditary and old age (ATTR and wild-type
transthyretin amyloid).
Diagnosis may be
suspected when
protein is
found in the urine...
- Wild-type
transthyretin amyloid (WTTA), also
known as
senile systemic amyloidosis (SSA), is a
disease that
typically affects the
heart and
tendons of...
-
medication used for the
treatment of the
polyneuropathy of
hereditary transthyretin-mediated (hATTR)
amyloidosis in adults. It is a
double stranded small...
- of
transthyretin-mediated amyloidosis. It is a
transthyretin-directed
antisense oligonucleotide. It was
developed to
treat hereditary transthyretin amyloidosis...
-
Familial amyloid polyneuropathy, also
called hereditary transthyretin amyloidosis (hATTR), or
Corino de Andrade's disease, is an
autosomal dominant neurodegenerative...
- the
quaternary structure of the
protein transthyretin. In
people with
transthyretin amyloidosis,
transthyretin falls apart and
forms clumps called (amyloid)...
-
familial transthyretin mutations,
liver transplantation can
provide the body with a
source of
normal transthyretin. By
changing the
source of
transthyretin from...
- (FAC), or
transthyretin amyloid cardiomyopathy (ATTR-CM)
results from the
aggregation and
deposition of
mutant and wild-type
transthyretin (TTR) protein...
- (>90%)
transthyretin stabilizer,
developed to
mimic the
protective properties of the naturally-occurring T119M mutation, to
treat transthyretin amyloid...
