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Synaptotagmins (SYTs)
constitute a
family of membrane-trafficking
proteins that are
characterized by an N-terminal
transmembrane region (TMR), a variable...
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Synaptotagmin-1 is a
protein that in
humans is
encoded by the SYT1 gene.
Synaptotagmins are
integral membrane proteins of
synaptic vesicles thought to...
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Extended synaptotagmin-2 is a
protein that in
humans is
encoded by the ESYT2 gene. GRCh38:
Ensembl release 89: ENSG00000117868 – Ensembl, May 2017 GRCm38:...
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Extended synaptotagmin-1 is a
protein in
humans that is
encoded by the ESYT1 gene. GRCh38:
Ensembl release 89: ENSG00000139641 – Ensembl, May 2017 GRCm38:...
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Synaptotagmin-7 is a
protein that in
humans is
encoded by the SYT7 gene.
Synaptotagmins, such as SYT7, are calcium-dependent phospholipid-binding proteins...
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Synaptotagmin-13 is a
protein that in
humans is
encoded by the SYT13 gene. SYT13
belongs to the
large synaptotagmin protein family. All synaptotagmins...
- gradient.
Calcium goes on to
stimulate exocytosis via
binding with
synaptotagmin 1. SNAP-25 however, has been
shown to
negatively regulate VGCC function...
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synaphin 1 and 2. In the
presence of Ca2+, the
transport vesicle protein synaptotagmin displaces complexin,
allowing the
SNARE protein complex to bind the...
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Synaptotagmin-5 is a
protein that in
humans is
encoded by the SYT5 gene. GRCh38:
Ensembl release 89: ENSG00000129990 – Ensembl, May 2017 GRCm38: Ensembl...
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fusing membranes.
Synaptotagmin has been
recognized as the
major sensor for Ca2+
triggered exocytosis in animals. However,
synaptotagmin proteins are absent...
