-
Succinylacetone is a
chemical compound that is
formed by the
oxidation of
glycine and is a
precursor of methylglyoxal. It is a
pathognomonic compound...
-
blood tests for the
presence of a
fumarylacetoacetate metabolite,
succinylacetone,
which is
considered a
pathognomonic indicator for the disease. Type...
-
molecules can
inhibit heme via
different mechanisms. For instance,
succinylacetone has been
shown to
decrease heme
concentrations by
inhibiting δ-aminolevulinic...
-
apoptosis in high concentrations. HT1 is
diagnosed when
elevated levels of
succinylacetone (SA), one of the
metabolites in this pathway, is
detected in blood...
- pain and
kidney disease in a
child with Henoch–Schönlein purpura, or
succinylacetone for
Tyrosinemia Type I.[citation needed] As
opposed to
symptoms (reported...
- biotinidase,
treatment with NTBC in
Tyrosinemia to
inhibit the
production of
succinylacetone which causes liver toxicity, and the use of
sodium benzoate to decrease...
-
specific test for
making a
diagnosis of ADP. Both lead
poisoning and
succinylacetone,
whose levels are
increased in
tyrosinemia type I,
inhibit ALAD. Therefore...
- 15-deoxy-Δ12,14
prostaglandin J2, nitro-oleic acid,
hydrogen peroxide, and
succinylacetone. HMOX1 is
inhibited by
certain porphyrins such as zinc protoporphyrin...
- 4-maleylacetoacetate
isomerase resulted in ac****ulation of
fumarylacetoacetate and
succinylacetone in the urine, but
individuals were
otherwise healthy. It is likely...
- specifically,
leads to the
amalgamation of
maleylacetoacetate and
succinylacetone which has been
observed to
cause oxidative stress. Also, scarcities...
