Definition of Sortilin. Meaning of Sortilin. Synonyms of Sortilin

- Sortilin (SORT1) is a protein that in humans is encoded by the SORT1 gene on chromosome 1. This protein is a type I membrane glycoprotein in the vacuolar...
- and Bak. The importance of sortilin in p75NTR-mediated apoptosis is exhibited by the fact that the inhibition of sortilin expression in neurons expressing...
- surface expression of low-affinity nerve growth factor receptor (p75). Sortilin is required for many apoptosis-promoting p75NTR reactions, functioning...
- Sortilin-related receptor, L(DLR class) A repeats containing is a protein that in humans is encoded by the SORL1 gene. SORL1 (also known as SORLA, SORLA1...
- The SorCS2 (sortilin-related Vps10p domain containing receptor 2) gene is found on chromosome 4 (4p16.1), and is composed of 28 exons. The N-terminal exons...
- and survival of the target neuron. High affinity binding between proNGF, sortilin, and p75NTR can result in either survival or programmed cell death. Study...
- amino acid change occurs on the portion of the prodomain where sortilin binds; and sortilin is essential for normal trafficking. The Val66Met mutation results...
- sleep-wake cycles, and dopamine. NTS3 is identical to the sorting protein sortilin and possesses many other functions outside the central nervous system....
- PCSK9 co-localizes with the protein sortilin on its way through the Golgi and trans-Golgi complex. A PCSK9-sortilin interaction is proposed to be required...
- SORL1 (which is also a receptor for other cargo proteins such as APP), and sortilin. Early study on sorting of acid hydrolases such as carboxypeptidase Y (CPY)...