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Somatomedins are a
group of
proteins produced predominantly by the
liver when
growth hormones act on
target tissue.
Somatomedins inhibit the
release of...
- A
somatomedin receptor is a
receptor which binds the
somatomedins (IGFs).
Somatomedin is
abbreviated to IGF, in
reference to insulin-like
growth factor...
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Somatomedin B is a
serum factor of
unknown function, is a
small cysteine-rich peptide,
derived proteolytically from the N-terminus of the cell-substrate...
- Insulin-like
growth factor 1 (IGF-1), also
called somatomedin C, is a
hormone similar in
molecular structure to
insulin which plays an
important role...
- des(1-3)IGF-1 Insulin-like
growth factor-1 (
somatomedin C) IGF-1 LR3 Insulin-like
growth factor-2 (
somatomedin A)
Insulin Mecasermin Mecasermin rinfabate...
- N-terminal domain. The
protein consists of
three domains: The N-terminal
Somatomedin B
domain (1-39) A
central domains with
hemopexin homology (131-342) A...
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Alterations in
somatomedin can
result in
growth hormone deficiency with two
known mechanisms;
failure of
tissues to
respond to
somatomedin, or
failure of...
-
deprivation or stress. The
symptoms include decreased growth hormone (GH) and
somatomedin secretion, very
short stature,
weight that is
inappropriate for the height...
-
disorder characterized by a lack of insulin-like
growth factor 1 (IGF-1;
somatomedin-C)
production in
response to
growth hormone (GH; hGH; somatotropin)....
- and the
subsequent stimulation of insulin-like
growth factor 1 (IGF-1;
somatomedin-1)
production by GH in
tissues such as, namely, the liver.
Other hypothalamic–pituitary...