- Sirolimus, also
known as
rapamycin and sold
under the
brand name
Rapamune among others, is a
macrolide compound that is used to coat
coronary stents,...
-
target of
rapamycin (mTOR), also
referred to as the
mechanistic target of
rapamycin, and
sometimes called FK506-binding
protein 12-
rapamycin-****ociated...
- mTORC1, also
known as
mammalian target of
rapamycin complex 1 or
mechanistic target of
rapamycin complex 1, is a
protein complex that
functions as a...
-
function by
inhibiting the
mammalian target of
rapamycin (mTOR) (also
known as the
mechanistic target of
rapamycin),
which is a serine/threonine-specific protein...
- mTOR
Complex 2 (mTORC2) is an
acutely rapamycin-insensitive
protein complex formed by serine/threonine
kinase mTOR that
regulates cell
proliferation and...
- had been
identified in 1993 as
conferring rapamycin resistance in
budding yeast, the
direct target of
rapamycin and its
mechanism of
action in
mammals was...
-
Methylprednisolone (Depo-Medrol, Medrol, Solu-Medrol) is a
synthetic glucocorticoid,
primarily prescribed for its anti-inflammatory and immunosuppressive...
-
glycogen and lipid." It has been
suggested that
rapamycin, a drug that
inhibits the
mechanistic Target Of
Rapamycin (mTOR) pathway,
might be a CR mimetic. based...
- and
works similarly to
sirolimus as an
inhibitor of
mammalian target of
rapamycin (mTOR). It is
marketed by
Novartis under the
trade names Zortress (US)...
- ****ociates with
rapamycin-insensitive
companion of mTOR (rictor), the
complex is
known as mTORC2 and it is
insensitive to
rapamycin. However, the complex...
